CoSpine Database_pain_dataset
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# Simultaneous cortico-spinal fMRI (CoSpine) Pain-dataset
**Version:** v1.1.0
**Date:** 2025-06-19
**BIDS-compliant**
---
## 1. Dataset overview
This is the first open-access, BIDS-compliant cortico-spinal task-based fMRI dataset. It enables exploration of cortical and spinal responses to thermal pain in healthy adults by providing simultaneous brain-and-spinal fMRI, physiological recordings, and behavioural ratings.
- **Task:** 4 s thermal pain stimuli followed by self-report ratings
- **Modalities:** fMRI (task-pain BOLD), T1-weighted structural MRI, field maps (GRE magnitude/phase, reversed phase-encoding B0), physiological signals (pulse & respiration), events/behavioural logs
- **Subjects:** 39
---
## 2. Experimental design
- **Pain stimulus:** contact thermode, temperatures 42–47 °C (subject-specific)
- **Ratings:**
- PR – pain intensity (0–10 VAS)
- UpR – unpleasantness (0–10 VAS)
> Full stimulus & rating onset/duration are recorded in each `*_events.tsv`.
---
## 3. Data acquisition
- **Scanner:** 3 T Siemens Prisma (Erlangen, Germany)
- **Coil:** Standard 64-channel head-neck coil
---
## 4. Dataset structure
```text
dataset/
├── dataset_description.json
├── README
├── task-pain_events.json
├── participants.tsv + .json
├── sub-01
│ ├── anat
│ │ ├── sub-01_T1w.json
│ │ └── sub-01_T1w.nii.gz
│ ├── fmap
│ │ ├── sub-01_acq-GRE_magnitude1.json
│ │ ├── sub-01_acq-GRE_magnitude1.nii.gz
│ │ ├── sub-01_acq-GRE_magnitude2.json
│ │ ├── sub-01_acq-GRE_magnitude2.nii.gz
│ │ ├── sub-01_acq-GRE_phase1.json
│ │ ├── sub-01_acq-GRE_phase1.nii.gz
│ │ ├── sub-01_dir-AP_epi.json
│ │ ├── sub-01_dir-AP_epi.nii.gz
│ │ ├── sub-01_dir-PA_epi.json
│ │ └── sub-01_dir-PA_epi.nii.gz
│ └── func
│ ├── sub-01_task-pain_bold.json
│ ├── sub-01_task-pain_bold.nii.gz
│ ├── sub-01_task-pain_dicom001_anonymized.IMA
│ ├── sub-01_task-pain_events.tsv
│ ├── sub-01_task-pain_recording-pulse_physio.json
│ ├── sub-01_task-pain_recording-pulse_physio.tsv.gz
│ ├── sub-01_task-pain_recording-respiratory_physio.json
│ └── sub-01_task-pain_recording-respiratory_physio.tsv.gz
├── derivatives/
│ └── preprocessed/
│ ├── dataset_description.json
│ └── sub-01/
```
---
## 5. Column & label definitions
**`*_events.tsv`**
| Column | Description |
|--------------|--------------------------------------|
| `trial_type` | `pain` = heat stimulus, `rating` = VAS response period |
| `PR` | Pain intensity (0–10) |
| `UpR` | Unpleasantness (0–10) |
**`participants.tsv`**
| Column | Units |
|-------------------|---------------|
| `age` | years |
| `sex` | m / f |
| `education` | years |
| `heat_temperature` | °C |
---
## 6. Quality control / preprocessing
- Structural images have been **defaced** to protect participant identity.
- Optimized preprocessing pipeline applied using:
- **FSL 6.0.7**
- **Spinal Cord Toolbox 5.9**
> Includes distortion correction (TOPUP) and physiological noise correction.
> Preprocessed data available in `derivatives/preprocessed/`.
---
## Contact
- **Zhaoxing Wei** – zhaoxing.wei@dartmouth.edu
- **Yazhuo Kong** – kongyz@psych.ac.cn
创建时间：
2025-01-27
