A small Jointly profiled 10X Genomics ATAC+GEX dataset on Human PBMCs

we will guide you through the process of inferring enhancer regulons, known as eRegulons, and enhancer-driven gene regulatory networks or eGRNs, utilizing the STREAM tool. Our demonstration leverages a select subset of data from the publicly accessible 10x Genomics Multiome dataset, specifically focusing on human Peripheral Blood Mononuclear Cells (PBMCs). For those interested in the comprehensive dataset, the raw data captured by the 10X Genomics Multiome ATAC+GEX can be downloaded directly from https://www.10xgenomics.com/resources/datasets/pbmc-from-a-healthy-donor-granulocytes-removed-through-cell-sorting-10-k-1-standard-1-0-0.本教程将指导您完整掌握利用STREAM工具推断增强子调控子（enhancer regulons，简称eRegulons）以及增强子驱动的基因调控网络（enhancer-driven gene regulatory networks，简称eGRNs）的全过程。本次演示采用公开可用的10x基因组学（10x Genomics）多组学数据集的精选子集，研究对象聚焦于人外周血单个核细胞（Peripheral Blood Mononuclear Cells，简称PBMCs）。若您希望获取完整数据集，可直接通过以下链接下载由10x Genomics Multiome ATAC+GEX捕获的原始数据：https://www.10xgenomics.com/resources/datasets/pbmc-from-a-healthy-donor-granulocytes-removed-through-cell-sorting-10-k-1-standard-1-0-0。