Additional file 2: of Continual reassessment method for dose escalation clinical trials in oncology: a comparison of prior skeleton approaches using AZD3514 data
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Final dose toxicity curves and 95 % prediction intervals for every CRM method + 10 percentage points. Legend: The predicted probabilities of experiencing a DLT and corresponding 95 % prediction intervals for each prior skeleton + 10 % approach used in the extended CRM method after the MTD has been determined for the AZD3514 data. (ZIP 678 kb)
针对每一种持续再评估法（Continual Reassessment Method, CRM）构建的最终剂量毒性曲线及95%预测区间（上浮10个百分点）。图例：针对AZD3514数据集确定最大耐受剂量（Maximum Tolerated Dose, MTD）后，拓展版持续再评估法中所采用的每一种先验骨架上浮10%方案对应的剂量限制性毒性（Dose-Limiting Toxicity, DLT）发生预测概率，及其对应的95%预测区间。（ZIP 678 kb）
创建时间：
2016-12-14
