Cryo-EM structure of ACKR3 in complex with CXCL12 and an intracellular Fab Descriptor: Anti-Fab nanobody, Atypical chemokine receptor 3, CHOLESTEROL, ... Authors: Yen, Y.C, Schafer, C.T, Gustavsson, M
Our results identified that CXCL12-mediated H3K9 methylation impacted on the global chromatin in the transcriptional profile of T-ALL cells. Overall design: Jurkat cells (T-ALL cell line) were used fo
G protein-coupled receptors (GPCRs) interact with many transducers like G proteins and β-arrestins. Some GPCR agonists act as “biased agonists” which preferentially activate specific signaling transdu
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19) pandemic, represents a global crisis. Most patients developed mild/m
