Effects of etravirine on HIV-1 reverse transcriptase, recovered from plasma of HIV-1 infected patients.

*Two recombinant reverse transcriptase, (BH10)-wild-type (WT) and its mutant form L100I, were used as references. Based on the IC50 value of BH10-wild-type (1.0±0.18 µM), which was included in every run, the IC50 value and the fold-difference in susceptibility of each isolate were determined. A fold-difference of Abbreviations: NA, not applicable; IC50, inhibitory effect; ETR etravirine.**Genotype result was obtained six months earlier. The results of three genotypic scoring systems (Stanford, Monogram Weighted Score, Tibotec Weighted Genotype Score) predicting ETR susceptibility are presented. s: sensitive; i: intermediate; r: resistant. A Stanford score of 0-