A controlled quasi-experimental study of an educational intervention to reduce the unnecessary use of antimicrobials for asymptomatic bacteriuria

Background: Asymptomatic bacteriuria (ABU) should only be treated in cases of pregnancy or in-patients undergoing urologic procedures; however, unnecessary treatment of ABU is common in clinical practice. Objective: To identify risk factors for unnecessary treatment and to assess the impact of an educational intervention focused on these risk factors on treatment of ABU. Design: Quasi-experimental study with a control group. Setting: Two tertiary teaching adult care hospitals. Participants: Consecutive patients with positive urine cultures between January 30th and April 17th, 2012 (baseline) and January 30th and April 30th, 2013 (intervention). Intervention: In January 2013, a multifaceted educational intervention based on risk factors identified during the baseline period was provided to medical residents (monthly) on one clinical teaching unit (CTU) at one hospital site, with the CTU of the other hospital serving as the control. Results: During the baseline period, 160/341 (46.9%) pos...

背景：无症状菌尿症（Asymptomatic bacteriuria, ABU）仅需在妊娠患者或接受泌尿外科手术的住院患者中开展治疗；然而临床实践中对无症状菌尿症的过度治疗仍较为普遍。研究目标：明确无症状菌尿症过度治疗的危险因素，并评估针对此类危险因素开展的教育干预对无症状菌尿症治疗行为的影响。研究设计：设对照组的类实验研究。研究地点：两所成人三级教学医院。研究对象：2012年1月30日至4月17日（基线期）以及2013年1月30日至4月30日（干预期）期间连续纳入的尿培养阳性患者。干预措施：2013年1月起，针对基线期明确的危险因素，在其中一所医院的一个临床教学单元（Clinical Teaching Unit, CTU）为住院医师开展每月一次的多维度教育干预，以另一所医院的临床教学单元作为对照。研究结果：基线期共有160/341（46.9%）阳性……