Two-cohort (Cambridge and EUGENDA) GWAS meta-analyses of FHR-4 and FH levels

The data repository consists of four files of summary statistics from the two-cohort (Cambridge and EUGENDA) GWAS meta-analyses of FH and FHR-4 levels: <br><b>METAANALYSIS_FH_ALL-adjAMD.txt </b>(tab-separated values file; size:<b> </b>448Mb)<b>METAANALYSIS_FH_controls.txt </b>(tab-separated values file; size:<b> </b>448Mb) <b>METAANALYSIS_FHR4_ALL-adjAMD.txt </b>(tab-separated values file; size:<b> </b>432Mb)<br> <b>METAANALYSIS_FHR4_controls.txt </b>(tab-separated values file; size:<b> </b>432Mb)<b><br></b>The single-cohort GWASs were carried out using EPACTS software available at http://genome.sph.umich.edu/wiki/EPACTS; effect size estimates and standard errors of single variants seen in both cohorts were subsequently combined in a fixed-effect meta-analysis using METAL software available at http://csg.sph.umich.edu/abecasis/metal/download/.<br>More details are provided in the <b>Readme.pdf </b>file.