Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide (ZNF831) and UDP-GlcNAc

Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide (ZNF831) and UDP-GlcNAc Descriptor: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, Zinc finger protein 831 Authors: Xie, J, Jiang, J. Deposit date: 2023-01-17 Release date: 2023-08-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.69 Å) Cite: Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase. Nat.Chem.Biol., 19, 2023人源O-连接β-N-乙酰葡糖胺转移酶（O-GlcNAc transferase, OGT）与外位点结合肽（ZNF831）及UDP-GlcNAc形成复合物的晶体结构 标识符：UDP-N-乙酰葡糖胺——肽N-乙酰葡糖胺基转移酶110kDa亚基、尿苷二磷酸-N-乙酰葡糖胺、锌指蛋白831 作者：Xie J, Jiang J 提交日期：2023-01-17 发布日期：2023-08-09 最后修改日期：2023-11-08 实验方法：X射线衍射（分辨率3.69 Å） 引用文献：《基序依赖的中间结构域结合调控O-GlcNAc转移酶》，Nat. Chem. Biol., 19, 2023