Characteristics of patients carrying <i>TET2</i>, <i>DNMT3A</i>, <i>ASXL1</i> and <i>CBL</i> family mutation.

WHO, World Health Organization; SM, systemic mastocytosis; ISM, indolent SM; SM-AHNMD, SM with associated non-mast cell lineage disease; ASM, aggressive SM; MSC, mast cell sarcoma; M, male; F, female; dx, diagnosis; Age, y, years; Neg., negative; Pos., positive. *UPD2pterp13.1 (homozygous mutation). †UPD4q12qter (homozygous mutation). ‡Germ-line confirmation. §Mutations reported at http://www.sanger.ac.uk. IIAssociated hematological non mast cell disease: chronic myelomonocytic leukemia. ¶Associated hematological non mast cell disease: chronic myelomonocytic leukemia and chronic lymphocytic leukemia.