A rational approach to the design of antihypertensives. X-ray studies of complexes between aspartic proteinases and aminoalcohol renin inhibitors

A rational approach to the design of antihypertensives. X-ray studies of complexes between aspartic proteinases and aminoalcohol renin inhibitors Descriptor: ENDOTHIAPEPSIN, methyl N-[(2S,3S)-3-amino-2-hydroxy-5-methylhexyl]-L-valyl-L-isoleucyl-L-phenylalaninate Authors: Cooper, J.B, Foundling, S.I, Blundell, T.L. Deposit date: 1990-11-07 Release date: 1991-01-15 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2 Å) Cite: A Rational Approach to the Design of Antihypertensives. X-Ray Studies of Complexes between Aspartic Proteinases and Aminoalcohol Renin Inhibitors Topics in Medicinal Chemistry, 1988

抗高血压药物设计的理性策略：天冬氨酸蛋白酶与氨基醇类肾素抑制剂复合物的X射线研究。描述符：内硫蛋白酶（ENDOTHIAPEPSIN）、N-[(2S,3S)-3-氨基-2-羟基-5-甲基己基]-L-缬氨酰-L-异亮氨酰-L-苯丙氨酸甲酯。作者：Cooper, J.B、Foundling, S.I、Blundell, T.L.。提交日期：1990-11-07。发布日期：1991-01-15。最后修改时间：2024-11-06。实验方法：X射线衍射（2 Å）。引用文献：《抗高血压药物设计的理性策略：天冬氨酸蛋白酶与氨基醇类肾素抑制剂复合物的X射线研究》，载于《药物化学专题（Topics in Medicinal Chemistry）》，1988年。