Intraspecies variability effect in the identification of targets and possible offtargets.

For each example, upper file shows the targets and offtargets listed by ARES-GT (with thresholds L0 = 4 and L1 = 3) for each reference genome. SNPs differences between genomes that explain why some targets or offtargets are not detected are shown in lower file (separated by discontinuous line) as red boxes. Black boxes mark mismatches with candidates sequence.