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Mapping triclabendazole resistance in Fasciola

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NIAID Data Ecosystem2026-03-13 收录
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The liver fluke Fasciola hepatica causes significant animal health and economic harm by reducing productivity of meat and dairy production in sheep and cattle. Triclabendazole (TCBZ) is the primary treatment used since it is effective against both juvenile and adult stages. We performed genetic mapping to localise the genomic region under selection, followed by analysis of field isolates and RNAseq to further validate and characterise the molecular bases of TCBZ resistance.

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2022-06-03
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