Baseline positivity of anal cytology and biomarkers by histologic anal diagnosis.

P values correspond to a comparison of the proportion of subjects with no SIL or LSIL versus those with HSIL, who were identified by each biomarker.SIL, squamous intraepithelial lesion; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; HPV, human papillomavirus.LSIL group included MSM with anal intraepithelial neoplasia (AIN) 1 on histology. HSIL group included MSM with AIN 2 or AIN 3 on histology. No SIL group included MSM without LSIL or HSIL.P值对应于每一种生物标志物所鉴定出的、无鳞状上皮内病变（squamous intraepithelial lesion, SIL）或低度鳞状上皮内病变（low-grade squamous intraepithelial lesion, LSIL）的受试者与高度鳞状上皮内病变（high-grade squamous intraepithelial lesion, HSIL）受试者的比例比较。SIL即鳞状上皮内病变；LSIL即低度鳞状上皮内病变；HSIL即高度鳞状上皮内病变；HPV即人乳头瘤病毒（human papillomavirus）。LSIL组纳入经组织学确诊为肛门上皮内瘤变（anal intraepithelial neoplasia, AIN）1级的男男性行为者（men who have sex with men, MSM）；HSIL组纳入经组织学确诊为AIN 2级或AIN 3级的男男性行为者；无SIL组纳入未检出LSIL或HSIL的男男性行为者。