Supplementary Materials for: A novel stratification framework based on vascular-fibrotic complications identifies distinct risk endotypes in systemic sclerosis: a retrospective cohort study.

This dataset contains supplementary tables (Tables S1–S2) for the article entitled "A novel stratification framework based on vascular-fibrotic complications identifies distinct risk endotypes in systemic sclerosis: a retrospective cohort study". Table S1 provides detailed comparative data on additional autoantibodies (including anti‑SSA, anti‑SSB, anti‑dsDNA, anti‑Sm, anti‑nRNP/Sm, anti‑nucleosome [ANuA], anti‑histone [AHA], and anti‑ribosomal P protein [anti‑Rib‑P]) across the four complication‑based subgroups (Vascular‑dominant, Fibrotic‑dominant, Mixed, and Limited). Table S2 presents echocardiographic parameters (left ventricular ejection fraction [LVEF], E/A ratio) and serum cardiac enzymes (creatine kinase [CK], CK‑MB, lactate dehydrogenase [LDH], hydroxybutyrate dehydrogenase [HBDH]) with available data. These supplementary materials support the findings reported in the main manuscript.

本数据集包含题为《基于血管纤维化并发症的新型分层框架可识别系统性硬化症中不同风险内型：一项回顾性队列研究》的学术论文的补充表（表S1~S2）。其中，表S1提供了4个基于并发症分型的亚组（血管优势型（Vascular-dominant）、纤维化优势型（Fibrotic-dominant）、混合型（Mixed）与局限型（Limited））中额外自身抗体（包括抗SSA、抗SSB、抗双链DNA（anti-dsDNA）、抗Sm、抗nRNP/Sm、抗核小体（ANuA）、抗组蛋白（AHA）以及抗核糖体P蛋白（anti-Rib-P））的详细对比数据；表S2则呈现了具备可用检测数据的超声心动图参数（左心室射血分数（left ventricular ejection fraction，LVEF）、E/A比值）与血清心肌酶指标（肌酸激酶（creatine kinase，CK）、CK-MB、乳酸脱氢酶（lactate dehydrogenase，LDH）、羟丁酸脱氢酶（hydroxybutyrate dehydrogenase，HBDH））。上述补充材料可为正文中报告的核心研究发现提供支撑。