Association studies for NPY gene exon 2 (+1128 T/C), promoter (−399 T/C) and IL1B gene promoter (−511 C/T) polymorphisms in active and stable vitiligo patients from Gujarat.

‘n’ represents number of Patients/ Controls, HWE refers to Hardy-Weinberg Equilibrium, (AV) refers to Active Vitiligo, (SV) refers to Stable Vitiligo, (C) refers to Controls and CI refers to Confidence Interval.aActive Vitiligo vs. Controls using the chi-squared test with 3×2 contingency table,bStable Vitiligo vs. Controls using the chi-squared test with 3×2 contingency table,cActive Vitiligo vs. Controls using the chi-squared test with 2×2 contingency table,dStable Vitiligo vs. Controls using the chi-squared test with 2×2 contingency table.Odds ratio is based on allele frequency distribution. Statistical significance was considered at p value ≤0.017 due to Bonferroni's correction for multiple testing.Association studies for NPY gene exon 2 (+1128 T/C), promoter (−399 T/C) and IL1B gene promoter (−511 C/T) polymorphisms in active and stable vitiligo patients from Gujarat.本数据集的符号定义如下：`n` 代表患者/对照的样本量；HWE 指哈迪-温伯格平衡（Hardy-Weinberg Equilibrium）；AV 指代活动期白癜风（Active Vitiligo）；SV 指代稳定期白癜风（Stable Vitiligo）；C 指代对照组（Controls）；CI 指代置信区间（Confidence Interval）。a. 采用3×2列联表卡方检验比较活动期白癜风患者与对照组；b. 采用3×2列联表卡方检验比较稳定期白癜风患者与对照组；c. 采用2×2列联表卡方检验比较活动期白癜风患者与对照组；d. 采用2×2列联表卡方检验比较稳定期白癜风患者与对照组。比值比（Odds ratio）基于等位基因频率分布计算得到。由于需对多重检验进行Bonferroni校正，本研究将p值≤0.017作为统计学显著性阈值。本数据集为来自古吉拉特邦的活动期与稳定期白癜风患者的NPY基因外显子2（+1128 T/C）、启动子区（-399 T/C）多态性，以及IL1B基因启动子区（-511 C/T）多态性的关联研究数据。