Annotating N termini for the human proteome project: N termini and Nα-acetylation status differentiate stable cleaved protein species from degradation remnants in the human erythrocyte proteome.

Data from ProteomeXchange, PXD ID: PXD000434. Experiment: 111213_RBC5_MG, file: 111213_RBC5_MG_Fr15_17.mzml. Published as part of J Proteome Res. 2014 Apr 4;13(4):2028-44 . From the Abstract: {{i}} Enucleated and largely void of internal membranes and organelles, erythrocytes are simple yet proteomically challenging cells due to the high hemoglobin content and wide dynamic range of protein concentrations that impedes protein identification. Using the N-terminomics procedure TAILS, we identified 1369 human erythrocyte natural and neo-N-termini and 1234 proteins. {{/i}}