Data and code pertaining to: Pangenomic decomposition reveals lineage-specific immune-evasion and virulence architectures in group A Streptococcus
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Data and code pertaining to Pangenomic decomposition reveals lineage-specific immune-evasion and virulence architectures in group A Streptococcus Jupyter notebooks containing all coded used to Obtain, Scrub, Explore, Model, and iNterpret Spyo-GENOMiCUS-400, a collection of 399 high-quality, complete S pyogenes genomes PanTA pangenome outputs Core, Accessory, and Rare genome partitions NMF outputs including the fully characterized L (genes x phylons) and A (phylon affinities x genomes) matrices
本数据集与配套代码聚焦泛基因组分解(Pangenomic decomposition)研究,揭示了A群链球菌(group A Streptococcus)中谱系特异性的免疫逃逸与毒力架构。 包含用于获取、清洗、探索、建模及解读Spyo-GENOMiCUS-400的全部代码的Jupyter Notebook文件;Spyo-GENOMiCUS-400为收录399条高质量完整化脓性链球菌(S pyogenes)基因组的数据集。 PanTA泛基因组分析输出文件 核心基因组、附属基因组与稀有基因组分区文件 非负矩阵分解(NMF)结果文件,包含已完成完整表征的L矩阵(基因×进化支)与A矩阵(进化支亲和性×基因组)



