Agonist bound human A2a adenosine receptor with D52N mutation at 2.60 A resolution

NIAID Data Ecosystem2026-05-02 收录

G蛋白偶联受体

药物靶点结构解析

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Agonist bound human A2a adenosine receptor with D52N mutation at 2.60 A resolution

创建时间：

2024-10-16

BTK in complex with 18A

BTK共价抑制剂

药物靶点结构解析

BTK in complex with 18A Descriptor: 2-(4-phenoxyphenoxy)-5-[(3R)-1-(prop-2-enoyl)piperidin-3-yl]pyridine-3-carboxamide, Tyrosine-protein kinase BTK Authors: Gardberg, A. Deposit date: 2021-06-22 Relea

Protein Data Bank Japan2024-11-06 更新70

Crystal Structure Analysis of human Macrophage Elastase MMP-12

蛋白质晶体学

药物靶点结构解析

Crystal Structure Analysis of human Macrophage Elastase MMP-12 Descriptor: CALCIUM ION, N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDE, ZINC ION, ... Aut

Protein Data Bank Japan2024-02-07 更新60

Cryo-EM structure of CD97/Gq complex

结构生物学

G蛋白偶联受体

Cryo-EM structure of CD97/Gq complex Descriptor: Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding prot

Protein Data Bank Japan2025-07-02 更新20

Crystal Structure of hTDO2 bound to inhibitor GNE1

蛋白质晶体学

药物靶点结构解析

Crystal Structure of hTDO2 bound to inhibitor GNE1 Descriptor: 1,5-anhydro-2,3-dideoxy-3-[(5S)-5H-imidazo[5,1-a]isoindol-5-yl]-D-threo-pentitol, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan 2,3-dioxyge

Protein Data Bank Japan2023-10-11 更新60

G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets.

血小板信号传导

G蛋白偶联受体

Using subtype-specific antisera, we were able to identify the recently described alpha subunits of G12 and G13 in platelet membranes as 43-kDa proteins. Activation of the thromboxane A2 and the thromb

PubMed Central1994-01-18 更新30

Agonist bound human A2a adenosine receptor with D52N mutation at 2.60 A resolution

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