The neoplastic cell senescence verified by two methods (BrdU incorporation assay and SA-β-Gal assay).

(A–C) Only two populations of cells are visible: BrdU(−)/SA-β-Gal(+)/TP53(+) and BrdU(+)/SA-β-Gal(−)/TP53(+).(图A至C) 仅可观测到两类细胞群：溴脱氧尿苷（BrdU）阴性/衰老相关β-半乳糖苷酶（SA-β-Gal）阳性/肿瘤蛋白p53（TP53）阳性，以及溴脱氧尿苷（BrdU）阳性/衰老相关β-半乳糖苷酶（SA-β-Gal）阴性/肿瘤蛋白p53（TP53）阳性。