Trypanocidal effect of Arylimidamides and Benznidazole against <i>T. cruzi</i> (Y strain).
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The activity of the compounds against bloodstream trypomastigotes (BT) and intracellular parasites was evaluated during their incubation at 37°C and at 4°C for 24 h and 48 h. All assays were run at least two times in duplicate. IC50 values = Compound concentration that reduces the number of parasites by 50%. SI* = selectivity index corresponds to the ratio LC50/IC50 – For BT and intracellular parasites calculated on LC50 values of 24 and 48 h of incubation at 37°C, respectively. Bz = Benznidazole.
创建时间：
2015-12-02
