DNA methylation profiling of kidney transplant recipients

Targeted bisulfite sequencing data of peripheral blood mononuclear cells (PBMCs) from participants pre- and post- kidney transplant(Tx) was generated to study 1) methylation difference between pre- and postTx, 2) methylation difference between cytomegalovirus (CMV) seropositive and seronegative in preTx, 3) immune response regarding Tx and immunosuppression prophylaxes, and 4) how the gene expression and DNA methylation are associated. We collected PBMC for targeted bisulfite sequencing from 135 kidney transplant patients with samples collected before and then 3 months after transplantation.