Crystal structure of the core catalytic domain of human inositol phosphate multikinase soaked with C4-analogue of PtdIns(4,5)P2 and ADP
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Crystal structure of the core catalytic domain of human inositol phosphate multikinase soaked with C4-analogue of PtdIns(4,5)P2 and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol polyphosphate multikinase,Inositol polyphosphate multikinase, ... Authors: Wang, H, Shears, S.B. Deposit date: 2017-06-06 Release date: 2017-09-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural features of human inositol phosphate multikinase rationalize its inositol phosphate kinase and phosphoinositide 3-kinase activities. J. Biol. Chem., 292, 2017
经磷脂酰肌醇-4,5-二磷酸(PtdIns(4,5)P2)的C4类似物与腺苷二磷酸(ADP)浸泡处理的人肌醇磷酸多激酶核心催化结构域的晶体结构。
描述项:腺苷-5'-二磷酸(ADENOSINE-5'-DIPHOSPHATE)、D-肌醇-1,4,5-三磷酸(D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE)、肌醇多磷酸多激酶(Inositol polyphosphate multikinase)……
作者:Wang H、Shears S.B.
提交日期:2017-06-06
发布日期:2017-09-13
最后修改日期:2024-03-13
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.6埃(Å)
引用文献:人肌醇磷酸多激酶的结构特征阐明其肌醇磷酸激酶与磷酸肌醇3-激酶活性,《J. Biol. Chem.》,292卷,2017年
创建时间:
2017-06-06



