A high-resolution multi-shell 3T diffusion magnetic resonance imaging dataset as part of the Amsterdam Ultra-high field adult lifespan database (AHEAD) - dataset

In order to further our understanding of brain function and the underlying networks, more advanced diffusion weighted magnetic resonance imaging (DW MRI) data are essential. Here we present freely available high-resolution multi-shell multi-directional 3 Tesla (T) DWI MRI data as part of the ‘Amsterdam Ultra-high field adult lifespan database’ (AHEAD). The 3T DWI AHEAD dataset include 1.28mm isotropic whole brain DWI data of 49 healthy adult participants between 18 and 90 years old. The acquired data include DWIs at three non-zero b-values (48 directions, b-value 700 s/mm2; 56 directions, b-value 1000 s/mm2; 64 directions, b-value 1600s/mm2) including a total of twelve volumes with a b-value of 0 s/mm2 (b0 volumes). In addition, eight b0 volumes with a reversed phase encoding direction were acquired to correct for distortions. To facilitate future use, the DWI data have been denoised, corrected for eddy currents, susceptibility-induced off-resonance field distortions, bias fields, and are skull stripped.为进一步深化对大脑功能及其潜在神经网络的理解，更为先进的扩散加权磁共振成像（diffusion weighted magnetic resonance imaging，DW MRI）数据不可或缺。在此，我们公开了可免费获取的高分辨率多壳层多方向3特斯拉（Tesla，T）扩散加权磁共振成像数据，该数据隶属于“阿姆斯特丹超高场成人寿命数据库”（Amsterdam Ultra-high field adult lifespan database，AHEAD）。本次发布的3T DWI AHEAD数据集涵盖了49名年龄介于18至90岁的健康成年受试者的1.28mm各向同性全脑扩散加权成像数据。所采集的数据包含三种非零b值（b-value）的扩散加权成像序列：b值为700 s/mm²时对应48个扩散方向，b值为1000 s/mm²时对应56个扩散方向，b值为1600 s/mm²时对应64个扩散方向，同时还包含总计12幅b值为0 s/mm²的图像（b0 volumes）。此外，我们还采集了8幅相位编码方向相反的b0图像，用于校正图像畸变。为便于后续研究应用，该扩散加权成像数据已完成去噪、涡流校正、磁化率诱导的离共振场畸变校正、偏场校正，并已完成颅骨剥离（skull stripping）。