Evaluation of the Biomedical Significance and Prognostic Value of Calcification in the Placenta

This project investigated whether placental vascular calcification is an early marker of placental dysfunction. Mineral homeostasis and ectopic deposition are regulated by complex pathways, both active and passive. In order to investigate ectopic mineralization pathways during pregnancy in normal and diseased conditions, our team first worked towards determining biological fluid concentrations of essential minerals which are consumed through dietary consumption, including calcium, magnesium, and phosphate (phosphorus). The enclosed datasets include experimentally determined biological fluid phosphate concentrations.