Oxysterols[M1] Suppress Release of DNA from Granulocytes into Extracellular Space After Stimulation with PhorbolMyristate Acetate[M1]The article title is different from the one submitted online at susy.mdpi.com. Please confirm which one is correct.
收藏Figshare2024-11-05 更新2026-04-08 收录
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In the present study, we examined the effects of four oxysterols on the release of DNA and proteins from neutrophils. Unexpectedly, oxysterols, but not cholesterol, suppressed DNA release from neutrophils. Furthermore, treatment of cells with methyl-β-cyclodextrin (MβCD) that extracts sterol compounds from cell membranes to form inclusion complexes enhanced DNA release from PMA-stimulated cells. These observations suggest that oxysterols may act as modulators of neutrophil activation.
提供机构：
Watanabe, Yuichi; Itabe, Hiroyuki; Makiyama, Tomohiko; Obama, Takashi
创建时间：
2024-11-05
