Anxiety, depression, health seeking behaviour and consulting for chronic pain in relation to the val158met COMT polymorphism among patients with IBS.

There was no significant difference in age, BMI, HADS scores, health seeking behavior and consulting for chronic pain between different genotypes among 70 patients (61 women) with IBS. However, the val/met carriers tended to have less HADS-depression score compared to the other genotypes and the met/met genotype tended have more visits per year in primary care and more chronic neck pain. BMI = Body mass index. HADS = Hospital anxiety depression scale. ns = Non-significant.*Statistically significant: p