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MS-based proteomics in HUVECs transfecting with IVT mRNA

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NIAID Data Ecosystem2026-05-10 收录
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https://www.omicsdi.org/dataset/pride/PXD061961
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The therapeutic success of in vitro-transcribed (IVT) mRNA depends on its stability and efficient translation. However, IVT mRNA is highly susceptible to immune-mediated degradation, limiting its efficacy. To investigate the binding protein profiles of IVT mRNA, we transfected HUVECs with 4SU-modified mRNA for 6h. LC-MS/MS was performed to identify the binding proteins of IVT mCherry mRNA.
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2026-03-23
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