Parameter inputs for a model-based analysis of potential HIV cure strategies.
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SD: standard deviation; QOL: quality-of-life.aDetermined through initialization run of simulated cohort; bFor 24 months based on vorinostat; cFor monthly antiretroviral therapy, derived from weighted averages of current therapies until gene- or chemo-therapy is complete; dFor immunosuppressive agents, including methotrexate with tacrolimus.Parameter inputs for a model-based analysis of potential HIV cure strategies.
SD:标准差(standard deviation);QOL:生活质量(quality-of-life)。a:经模拟队列的初始化运行确定;b:针对伏立诺他(vorinostat)相关的24个月疗程;c:针对每月给药的抗逆转录病毒疗法(antiretroviral therapy),其参数值为当前各类疗法的加权平均值,直至基因治疗或化疗完成;d:针对免疫抑制剂方案,包括甲氨蝶呤(methotrexate)与他克莫司(tacrolimus)联用。本内容为潜在HIV治愈策略的基于模型分析所需的参数输入。
创建时间:
2015-12-02



