Toxicity of QX-314 on central nervous system according to Racine's convulsive scale.

For each dose of QX-314, 10 rats were observed. Behavior of rats was scored according to Racine's score scale including score 0-5, as previously described [23], [24].针对QX-314的每一种给药剂量，均选取10只大鼠开展观测。大鼠的行为表现依据拉辛评分量表（Racine's score scale）进行评分，该量表涵盖0至5分的评分等级，相关方法如既往文献[23]、[24]所述。