Distribution of propranolol in water, biota and sediment.

Concentration of propranolol in water (μg l−1), biota (μg g ww−1) and sediment (μg g ww−1). Bioconcentration factor (BCF: (mg kg ww−1)/(mg l−1))) determined for mussels and amphipods and concentration factor (CF: (mg kg ww−1)/(mg l−1)) for sediment. Propranolol distribution (%) among the components in the microcosms (assuming a similar concentration in the algae as in the amphipods). Quantifications made after exposure to propranolol in 0 (Control); 100 μg l−1 (P100) and 1000 μg l−1 (P1000), mean±se. One mussel replicate from P1000 (one individual) showed a considerably higher concentration of propranolol (310 μg g ww−1) and BCF (295) than the other analysed individuals from the same treatment, and was excluded from the overall mean. LOQ = level of quantification, ww = wet weight.