RAGE engagement by SARS-CoV-2 enables monocyte infection and underlies COVID-19 severity
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.omicsdi.org/dataset/ega/EGAS00001007529
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The spread of SARS-CoV-2 has fuelled the COVID-19 pandemic with its enduring medical and socioeconomic challenges due to subsequent waves and long-term consequences of great concern. Here we chart the molecular basis of COVID-19 pathogenesis, by analysing patients’ immune response at single-cell resolution across disease course and severity. This approach confirms cell subpopulation-specific dysregulation in COVID-19 across disease course and severity and identifies a severity-associated activation of the receptor for advanced glycation endproduct (RAGE) pathway in monocytes.EGA study EGAS00001007529
创建时间：
2023-09-22
