Supplementary Material for: Case Report - Primary Conjunctival Embryonal Rhabdomyosarcoma in an 8 Year Old Girl

Introduction:

Rhabdomyosarcoma is a pediatric malignancy with the orbital soft tissues representing a significant anatomical region for this disease. However, rhabdomyosarcoma originating from the conjunctiva in pediatric population is a rare disease and this knowledge is essential in order to ensure prompt treatment and early intervention.

Case:

We discuss a rare case of primary conjunctival rhabdomyosarcoma in an 8 year old caucasian girl. She presents to paediatric ophthalmology clinic with 5 day history of rapidly growing conjunctival lesion in superior fornix of right eye. An urgent excisional biopsy was performed which yielded a large 30mm multilobulated, vascular papillomatous specimen with histopathological features consistent with embryonal rhabdomyosarcoma. She was promptly referred to oncology and was treated with systemic chemotherapy.

Conclusion:

Therapeutical options and prognosis of rhabdomyosarcomas are based on clinical tumour grouping, combined with histopathology staging and molecular features. Although rare, it is important to note that in the paediatric population, rhabdomyosarcoma can originate from the conjunctiva. Knowledge of its clinical, histopathological, and imaging characteristics is essential in order to achieve early diagnosis and timely treatment.