Intentional weight-loss strategies in obesity-related heart failure with preserved ejection fraction: reproducibility materials

Reproducibility materials supporting the systematic review and meta-analysis of intentional weight- and adiposity-reduction strategies in obesity-related heart failure with preserved ejection fraction. The deposit includes the final study-level dataset, extraction records, R analysis code and original execution outputs, outcome-specific RoB 2 assessments, GRADE evidence profiles, Summary of Findings tables, and trial-family mapping. No cross-mechanism pooled effect was calculated. Tirzepatide estimates were retained on their published scales, and peak oxygen consumption was not pooled because the available interventions and estimands were not sufficiently comparable.