Single cell analysis of sister blastomeres of 2-cell mouse embryos respecting pair associations. Mus musculus

Upon 2-cell embryo splitting, individual blastomeres were compared and contrasted with each other respecting pair associations (e.g. blastomere '1a' and '1b' of embryo 1, '2a' and '2b' of embryo 2, and so forth) Transcriptome analysis followed by cluster analysis (Ward) was able to match a minority of the blastomeres with the correct sister blastomere Overall design: Pair association (e.g. blastomere 'a' and 'b' from the same 2-cell embryo) was rigorously observed