CUT&RUN performed on CMK (ML-DS cell line) for GATA1s-HA-tag, H3K27ac, H3K27me3, and H3K4me3.
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CUT&RUN performed on CMK (ML-DS cell line) for GATA1s-HA-tag, H3K27ac, H3K27me3, and H3K4me3.As part of DLK1 is a GATA1s-Driven Dependency and Therapeutic Target in Down Syndrome-Associated Myeloid LeukemiaRunning title: Targeting DLK1 in ML-DS
本数据集对应于在CMK细胞系(ML-DS细胞系,ML-DS cell line)中针对GATA1s-HA标签(GATA1s-HA-tag)、组蛋白H3赖氨酸27乙酰化(H3K27ac)、组蛋白H3赖氨酸27三甲基化(H3K27me3)及组蛋白H3赖氨酸4三甲基化(H3K4me3)开展的靶标切割与释放测序(CUT&RUN)实验。该研究核心主题为:DLK1是唐氏综合征相关性髓系白血病(Down Syndrome-Associated Myeloid Leukemia)中由GATA1s驱动的致癌依赖靶点与治疗靶点,其论文短标题为:靶向ML-DS中的DLK1。
创建时间:
2026-01-23




