ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS

ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS Descriptor: 2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, CITRIC ACID, UROKINASE-TYPE PLASMINOGEN ACTIVATOR Authors: Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. Deposit date: 2001-04-27 Release date: 2002-04-27 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem.Biol., 8, 2001

靶向SER190类胰蛋白酶样丝氨酸蛋白酶药物靶点S1位点的高选择性抑制剂工程化研究
描述物：2-(2-羟基联苯基)-1H-苯并咪唑-5-甲脒、柠檬酸、尿激酶型纤溶酶原激活剂（urokinase-type plasminogen activator）
作者：Katz, B.A.、Sprengeler, P.A.、Luong, C.、Verner, E.、Spencer, J.R.、Breitenbucher, J.G.、Hui, H.、McGee, D.、Allen, D.、Martelli, A.、Mackman, R.L.
提交日期：2001-04-27
发布日期：2002-04-27
最后修改日期：2024-10-16
方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.9 Å
引用：《靶向SER190类胰蛋白酶样丝氨酸蛋白酶药物靶点S1位点的高选择性抑制剂》，《Chem.Biol.》，第8卷，2001年