Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121

NIAID Data Ecosystem2026-05-01 收录

CYP121底物特异性

结核分枝杆菌药物靶点

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Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121

创建时间：

2024-02-28

Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 26h

结核分枝杆菌药物靶点

片段药物发现

Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 26h Descriptor: 4,4'-(5-{[(1H-imidazol-4-yl)methyl]amino}-1H-pyrazole-3,4-diyl)diphenol, Cytochrome P450 121 CYP1

Protein Data Bank Japan2024-05-01 更新60

Crystal structure of M. tuberculosis KasA in complex with 4,4,4-trifluoro-N-(isoquinolin-6-yl)butane-1-sulfonamide

结核分枝杆菌药物靶点

蛋白质-配体复合物结构

Crystal structure of M. tuberculosis KasA in complex with 4,4,4-trifluoro-N-(isoquinolin-6-yl)butane-1-sulfonamide Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 1, 4,4,4-tris(fluoranyl)-~{N}-i

Protein Data Bank Japan2024-05-15 更新20

Mycobacterium tuberculosis methionyl-tRNA synthetase in complex with methionyl-adenylate

结核分枝杆菌药物靶点

酶结构解析

Mycobacterium tuberculosis methionyl-tRNA synthetase in complex with methionyl-adenylate Descriptor: Methionine-tRNA ligase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hyd

Protein Data Bank Japan2024-03-13 更新10

Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis complexed with CoA

PPAT-辅酶A复合物结构

结核分枝杆菌药物靶点

Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis complexed with CoA Descriptor: COENZYME A, Phosphopantetheine adenylyltransferase Authors: Timofeev, V.I, Smirnova, E.A, Chupova,

Protein Data Bank Japan2024-02-21 更新40

Structure of Mycobacterium tuberculosis ribosome recycling factor in presence of detergent

蛋白质结构解析

结核分枝杆菌药物靶点

Structure of Mycobacterium tuberculosis ribosome recycling factor in presence of detergent

NIAID Data Ecosystem20