Median rates of genome instability events (/10⁷ cell divisions).

The median rate (95% confidence of intervals) of the different genome instability events was measured as described in the text and in Fig. 1; the numbers in superscript (for example 6) correspond to the number of repeats. The MMS concentration was 1 mM as described under Material and methods. Allelic recombination, total LOH and chromosome loss were measured in diploid cells; chromosome gain was measured in haploid cells. The rates in the wpl1 mutants was previously found to not differ statistically from WT (also found there the rate for mcd1-1 haploid cells [15]). ND – not determined. * indicates a rate lower than indicated, a rate of 5 events per 108 cell divisions was a rate that could be accurately measured using this assay. Median rates of genome instability events (/107 cell divisions).