Genetic variants of the Nrf2/ARE pathway on the risk of anti-tuberculosis drug-induced liver injury: a systematic review - supplementary material

Table S1. Search strategies and results Table S2. Quality assessment of the included studies (NOS) Figure S1. Forest plot of AT-DILI risk associated with rs2001350 polymorphism in NFE2L2 of Nrf2/ARE pathway under different genetic model Figure S2. Forest plot of AT-DILI risk associated with rs6726395 polymorphism in NFE2L2 of Nrf2/ARE pathway under different genetic model Figure S3. Forest plot of AT-DILI risk associated with rs2070401 polymorphism in BACH1 of Nrf2/ARE pathway under different genetic model Figure S4. Forest plot of AT-DILI risk associated with 14 SNPs polymorphism (reported by 2 different studies) in the Nrf2/ARE pathway (dominant model) Figure S5. Forest plot of AT-DILI risk associated with 14 SNPs polymorphism (reported by 2 different studies) in the Nrf2/ARE pathway (recessive model) Figure S6. Forest plot of AT-DILI risk associated with 14 SNPs polymorphism (reported by 2 different studies) in the Nrf2/ARE pathway (allele model) Figure S7. Risk of bias of the included studies.补充表S1. 检索策略与结果 补充表S2. 纳入研究的质量评价（NOS） 补充图S1. 不同遗传模型下，Nrf2/ARE通路中NFE2L2基因（Nuclear Factor Erythroid 2-related Factor 2, NFE2L2）rs2001350多态性与抗结核药物性肝损伤（Anti-Tuberculosis Drug-Induced Liver Injury, AT-DILI）发病风险相关性的森林图 补充图S2. 不同遗传模型下，Nrf2/ARE通路中NFE2L2基因rs6726395多态性与AT-DILI发病风险相关性的森林图 补充图S3. 不同遗传模型下，Nrf2/ARE通路中BACH1基因（BTB and CNC Homolog 1, BACH1）rs2070401多态性与AT-DILI发病风险相关性的森林图 补充图S4. 显性遗传模型下，Nrf2/ARE通路中14个单核苷酸多态性（Single Nucleotide Polymorphisms, SNPs，由2项不同研究报道）与AT-DILI发病风险相关性的森林图 补充图S5. 隐性遗传模型下，Nrf2/ARE通路中14个SNPs多态性（由2项不同研究报道）与AT-DILI发病风险相关性的森林图 补充图S6. 等位基因遗传模型下，Nrf2/ARE通路中14个SNPs多态性（由2项不同研究报道）与AT-DILI发病风险相关性的森林图 补充图S7. 纳入研究的偏倚风险图