Expression data from fetal membranes. Homo sapiens

Genome wide expression profiling was used to identify signifnificantly changed genes in fetal membranes after GBS treatment Genome-wide expression profiles in GBS-inoculated human extraplacental membranes in vitro were used to identify transcriptomic pathways altered by GBS . Using bioinformatics analysis of these expression profiles we aimed to test our hypothesis that GBS activates pathways related to inflammation and premature birth in human extraplacental membranes. Overall design: RNA was analyzed using membranes obtained from 4 separate women for each condition (GBS treated and controls) and for each timepoint (4, 8 and 24 hours) for a total of 24 total samples.