Unfractionated, Aβ- and Cibacron blue-isolated human IgGs binding to plate-immobilized PFs.

1Mon stands for IgG monomers.2,3SEC-isolated IgG monomers (mon), dimers, and HMW aggregates as shown in Figs 2 & 3.Each value for EC50 and maximum signal amplitude was determined from the average of two to three sigmoidal fitted antibody binding curves, as shown in Figs 3 and 8.1Mon指代免疫球蛋白G单体（IgG monomers）。经文献2、3所述的尺寸排阻色谱（Size Exclusion Chromatography，SEC）分离得到的IgG单体（mon）、二聚体及高分子量聚集体（HMW aggregates），如图2与图3所示。半数效应浓度（median effective concentration，EC50）与最大信号振幅的各数值，均通过2至3条经S型拟合（sigmoidal fitted）的抗体结合曲线的平均值计算得到，如图3与图8所示。