Resveratrol protects ammonia-induced cytokines release through ERK signaling pathway.

C6 astroglial cells were incubated with 5 µM MEK/ERK inhibitor (PD98059– referred in the table as PD), followed by treatment with 100 µM resveratrol (RSV) and 5 mM ammonia for 24 h. Data are expressed as percentage of control values and represent means ± S.E.M of three experimental determinations performed in triplicate, analyzed statistically by two-way ANOVA followed by the Tukey’s test. (a) indicates significant differences from the control (P将C6星形胶质细胞与5 μM的丝裂原活化蛋白激酶激酶/细胞外调节蛋白激酶（MEK/ERK）抑制剂PD98059（表中简称为PD）孵育，随后予以100 μM白藜芦醇（RSV）与5 mM氨处理24小时。实验数据以对照组数值的百分比形式呈现，结果为三次独立实验测定（每次均进行三次技术重复）的均值±标准误（S.E.M.），所有数据均通过双因素方差分析（two-way ANOVA）结合Tukey检验完成统计学分析。(a) 代表与对照组存在显著差异（P