相关数据集
SWI/SNF Associates with Nascent Pre-mRNPs and Regulates Alternative Pre-mRNA Processing
The SWI/SNF chromatin remodeling complexes regulate the transcription of many genes by remodeling nucleosomes at promoter regions. In Drosophila, SWI/SNF plays an important role in ecdysone-dependent
NIAID Data Ecosystem90
Comparison of PPIE knockdown in HEK293T cells compared to scrambled shRNA control. Comparison of PPIE knockdown in HEK293T cells compared to scrambled shRNA control
HEK293T cells transduced with shRNA from MISSION library TRCN0000049368 using lentiviral delivery system. HEK293T cells transduced with scrambled shRNA, gifted from Dr. Mauricio Reginato. Tara L Davis
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A lncRNA, SPRIGHTLY, interacts with Polypyrimidine Tract Binding Protein 1 (PTBP1) and modulates SET And MYND Domain Containing 3 (SMYD3) exon skipping.
During the course of surveying Medulloblastoma (MB) group specific lncRNAs, we found that SPRIGHTLY was highly upregulated in group 4 cell lines and patient derived xenografts (PDX). Its knock down re
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GIGYF2 immunoprecipitation and mass spectrometry with RNase or spliceostatin A treatment.
Immunoaffinity purification/mass spectrometry analyses of StrepII-GIGYF2 from untreated, RNase A and SSA treated HEK293T cells. Label free quantification (LFQ) intensities along with the average fold
Figshare2021-10-19 更新30
LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity [iCLIP]. LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity [iCLIP]
RNA splicing plays a critical role in post-transcriptional gene regulation. Exponential expansion of intron length poses a challenge for accurate splicing. Little is known about how cells prevent inad
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