Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines.

To identify altered pathways in SCA28 LCLs, we performed a whole genome expression profiling, based on Affymetrix Human Genome U133A 2.0 Chip Array, on LCLs from four unrelated patients, each carrying a different AFG3L2 mutation. Gene expression profiling of 4 patients and 6 healthy controls