Effect of NFAT5 deficiency on gene expression in BV2 cells

Tonicity-Responsive Enhancer-Binding Protein (NFAT5), also known as Tonicity-Responsive Enhancer Binding Protein (TonEBP), is a important transcription factor in the regulation of osmoprotective and inflammatory genes. NFAT5 has been reported to regulate the pathological processes of inflammatory and autoimmune disorders. Our data provides a insight to the gene expression in NFAT5 deficiency BV2 microglia cells, which NFAT5 knocked down by sh-RNA. We performed comparative gene expression profiling analysis of RNA-Seq data from BV2 microglia RNA samples, which transfected with scambled sh-RNA (NC) or NFAT5 sh-RNA.