Microtubule Motor KIF3A Regulates Pulmonary Innate Defenses to Aspergillus and Influenza A Virus

Susceptibility to respiratory infection, decreased barrier function, impaired epithelial regeneration and enhanced inflammation are likely to contribute to the association between the KIF3A gene and asthma pathogenesis. Overall design: Kif3a deficient mice were chronicle or acutely exposed to aspergillus extract and then loss of Kif3a was assessed by Epcam sorted RNA Seq