Crystal structure of Escherichia coli 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with butylthio-DADMe-Immucillin-A

Crystal structure of Escherichia coli 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with butylthio-DADMe-Immucillin-A Descriptor: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, TETRAETHYLENE GLYCOL Authors: Cameron, S.A, Thomas, K, Almo, S.C, Schramm, V.L. Deposit date: 2014-10-02 Release date: 2015-08-19 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Active site and remote contributions to catalysis in methylthioadenosine nucleosidases. Biochemistry, 54, 2015

大肠杆菌5'-甲硫基腺苷/S-腺苷同型半胱氨酸核苷酶（MTAN）与丁硫基-DADMe-Immucillin-A结合的晶体结构。描述：(3R,4S)-1-[(4-氨基-5H-吡咯并[3,2-d]嘧啶-7-基)甲基]-4-[(丁基硫基)甲基]吡咯烷-3-醇、5'-甲硫基腺苷/S-腺苷同型半胱氨酸核苷酶、四甘醇（TETRAETHYLENE GLYCOL）。作者：Cameron, S.A、Thomas, K、Almo, S.C、Schramm, V.L.。提交日期：2014-10-02；发布日期：2015-08-19；最后修改日期：2023-09-27。实验方法：X射线衍射（1.64埃）。引用文献：《甲基硫代腺苷核苷酶的活性位点与远端催化贡献》，《生物化学》，第54卷，2015年。