Global RNA sequencing analysis of brown fat (BAT), inguinal white fat (iWAT), liver and muscle (quadriceps) of high-fat diet fed WT, FGF21 KO, UCP1 KO and UCP1/FGF21 double KO mice. Overall design: Th
Recent studies suggested the persistence of brown adipocytes in adult humans, as opposed to being exclusively present in infancy. In this study, we investigated the presence of brown-like adipocytes i
GLP-1 and GLP-2 (GLPs) are intestinal hormones with a key role in the homeostatic regulation of glucose metabolism and food intake. Their secretion by intestinal cells in response to food ingestion is
Toll-like receptors/Interleukin-1 receptor (IL-1R) signaling plays an important role in High-fat diet (HFD)-induced adipose tissue dysfunction contributing to obesity-associated metabolic syndromes. H
Single-cell transcriptomics reveals myeloid-specific PRMT1 deletion-mediated obesity remission and distinct spatiotemporal distributions of cell types in epididymal adipose tissue in a high-fat diet
