Crystal structure of human STING complexed with compound BSP17

Crystal structure of human STING complexed with compound BSP17 Descriptor: 4-[6-methoxy-5-[3-[[6-methoxy-2-(4-oxidanyl-4-oxidanylidene-butanoyl)-1-benzoselenophen-5-yl]oxy]propoxy]-1-benzoselenophen-2-yl]-4-oxidanylidene-butanoic acid, Stimulator of interferon genes protein Authors: Pan, L, Guan, X, Feng, X, Li, Z, Bian, J. Deposit date: 2022-03-15 Release date: 2023-03-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Discovery of Selenium-containing STING agonists as orally available anti tumor agents To be published人类STING (Stimulator of interferon genes protein，干扰素基因刺激蛋白)与化合物BSP17结合的晶体结构 描述：4-[6-甲氧基-5-[3-[[6-甲氧基-2-(4-羟基-4-氧代丁酰基)-1-苯并硒吩-5-基]氧基]丙氧基]-1-苯并硒吩-2-基]-4-氧代丁酸 作者：Pan L、Guan X、Feng X、Li Z、Bian J 提交日期：2022-03-15 发布日期：2023-03-22 最后修改日期：2023-11-29 检测方法：X射线衍射（分辨率2.7 Å） 引用文献：《含硒STING激动剂的发现：可口服抗肿瘤剂》（待发表）