Meta-analysis of fat distribution traits in UK Biobank; meta-analysis output
收藏资源简介:
Some of my previously-uploaded files round a small number of p-values to zero. Uploading the METAL output so that the rounding errors can be avoided. Columns: SNP: rs identifier with reference and alternate alleles appended Allele1: first allele Allele2: second allele Freq1 frequency of the variant collapsed across strata FreqSE: standard error of the frequency estimate MinFreq: minimum frequency MaxFreq: maximum frequency Effect: beta of the SNP StdErr: standard error P-value Direction: direction of effect in each stratum (UK Biobank, GIANT)
此前上传的部分文件将少量P值四舍五入至0。本次上传METAL输出结果以规避此类舍入误差。 字段说明如下: SNP:后缀附加参考等位基因与替代等位基因的rs编号标识符 Allele1:第一等位基因 Allele2:第二等位基因 Freq1:跨研究分层合并后的变异等位基因频率 FreqSE:频率估计值的标准误 MinFreq:最小等位基因频率 MaxFreq:最大等位基因频率 Effect:单核苷酸多态性(Single Nucleotide Polymorphism, SNP)的效应值β StdErr:标准误 P-value:P值 Direction:各研究分层(英国生物样本库UK Biobank、GIANT联盟)中的效应方向



